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Taken as a whole, the study points to potential dangers of overconsumption when the drug is used to treat menopause and some women with postmenopausal pain.
"This Valacyclovir generic price is the first clinical study to report that Sildenafil is associated with an increased risk of cancer and other reproductive tract diseases," the researchers write. study appears in The BMJ.
For example, the risk of ovarian cancer and bladder was increased by an estimated two and a half times four respectively, according to the findings in BMJ today.
Sildenafil, sold as Viagra, has become a popular over-the-counter supplement for treating menopausal symptoms such as hot flushes and vaginal dryness, as well menopause symptoms that include tiredness and lack of energy, the researchers note.
In fact, some women who took Viagra without a prescription may have inadvertently taken Sildenafil, leading to elevated blood levels of the drug, according to study.
"In general, we know that the use of Sildenafil may be harmful to women," said Professor Robert sildenafil vendita online Spitzer, of Endocrinology at Harvard School Public Health. "Given the strong evidence from previous small-scale studies, Pharmacy shop online germany we thought this was worth taking a closer look at the safety of Sildenafil for its own clinical application."
Sildenafil works by increasing the release of protein luteinizing hormone (LH), a widely thought to increase levels of estrogen, an estrogen that can increase breast cancer risks, the researchers say.
"For the past 20 years, we have thought that women's sex drive and desire go up during menopause. What we now know is that Sildenafil, which increases this protein, breast cancer risk," Professor Spitzer explained.
Professor Spitzer and his colleagues found that at least nine out of 10 women who had been taking Sildenafil detectable concentrations of the drug in their blood, and women had elevated levels of plasma FSH and LH levels.
A study with menopausal women in Sweden found that a quarter of women reported high levels Sildenafil in their urine and nine out of ten women with ovarian cancer also had elevated levels of Sildenafil in their urine and blood, the researchers added. a large study of women with breast cancer and their spouses' blood found that those with elevated levels of Sildenafil in their urine and blood were also at increased risk of developing cancer after they had their tumors.
The researchers acknowledge that there were a number of potential limitations to the study.
Professor Spitzer said there may be some dose-dependent effects. "We don't know when a person who's taking it might be at risk or not risk," he said.
- North Vernon
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Sildenafil relaxes muscles and increases blood flow to particular areas of the body. Sildenafil under the name Viagra is used to treat erectile dysfunction (impotence) in men. Another brand of sildenafil is Revatio, which is used to treat pulmonary arterial hypertension and improve exercise capacity in men and women. Do not take Viagra while also taking Revatio, unless your doctor tells you to. Sildenafil may also be used for purposes not listed in this medication guide.
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